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Lúcia Silva
    Biodegradability enhancement and detoxification of cork boiling wastewater (CBW) are required for the successful implementation of biological treatment options. We studied the possibility of achieving these goals through ozonation... more
    Biodegradability enhancement and detoxification of cork boiling wastewater (CBW) are required for the successful implementation of biological treatment options. We studied the possibility of achieving these goals through ozonation pre-treatment by experimenting on the effect of ozone dose and pH. The CBW used had a pH of 5.81, a chemical oxygen demand (COD) of 1,865 mg L1, a biochemical oxygen demand (BOD5) of 498 mg L1 and total phenol (TP) and tannin compounds concentrations of 523 and 399 mg L1, respectively. The ozone doses ranged from 0.27 to 2.63 for the O3(applied)/COD0 ratios with samples at natural pH and set to 3.33 and 9.96. Ozonation allowed the BOD20/COD ratio (biodegradability index) to increase from 0.37 to 0.63 and a toxicity reduction from 3.08 to 1.24 TU (Microtox). The corresponding removals obtained were 15.2–62.0%, 38.4–83.2% and 56.7–92.1% for COD, TP and colour, respectively. The best outcome of ozonation pre-treatment requires O3(applied)/COD0 ratios over 1.5 and an acid pH. The increase of TP removals with ozone dose at acid pH led to biodegradability enhancement and CBW detoxification. However, for similar conditions the highest COD removals were obtained at alkaline pH due to the hydroxyl radicals’ high oxidation ability but lack of selectivity.
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    A new diterpenic lactone has been synthesized starting from ent-hydrohalimic acid and its biological activity has been tested. A new dilactone 1 (5-epi-13-ent-halimen-18,10;15,16-diolide) has been synthesized from ent-hydrohalimic acid... more
    A new diterpenic lactone has been synthesized starting from ent-hydrohalimic acid and its biological activity has been tested.

    A new dilactone 1 (5-epi-13-ent-halimen-18,10;15,16-diolide) has been synthesized from ent-hydrohalimic acid 3.
    A new diterpenic lactone has been synthesized starting from ent-hydrohalimic acid and its biological activity has been tested. A new dilactone 1 (5-epi-13-ent-halimen-18,10;15,16-diolide) has been synthesized from ent-hydrohalimic acid... more
    A new diterpenic lactone has been synthesized starting from ent-hydrohalimic acid and its biological activity has been tested.

    A new dilactone 1 (5-epi-13-ent-halimen-18,10;15,16-diolide) has been synthesized from ent-hydrohalimic acid 3.
    A new diterpenic lactone has been synthesized starting from ent-hydrohalimic acid and its biological activity has been tested. A new dilactone 1 (5-epi-13-ent-halimen-18,10;15,16-diolide) has been synthesized from ent-hydrohalimic acid... more
    A new diterpenic lactone has been synthesized starting from ent-hydrohalimic acid and its biological activity has been tested.

    A new dilactone 1 (5-epi-13-ent-halimen-18,10;15,16-diolide) has been synthesized from ent-hydrohalimic acid 3.
    A bicyclic diterpene triol with a new rearranged labdane carbon skeleton was isolated from the aerial parts of Halimium viscosum (Willk.) Pinto da Silva (S. João da Pesqueira). Its structure was established by FAB MS and two-dimensional... more
    A bicyclic diterpene triol with a new rearranged labdane carbon skeleton was isolated from the aerial parts of Halimium viscosum (Willk.) Pinto da Silva (S. João da Pesqueira). Its structure was established by FAB MS and two-dimensional NMR experiments (1H/1H, 1H/13C) and its stereochemistry by NOE and X-ray study.

    A bicyclic diterpene triol, 5, with a new rearranged labdane carbon skeleton was isolated from the aerial parts of Halimium viscosum (S. João da Pesqueira). Its structure was established by FAB MS and two-dimensional NMR experiments and its stereochemistry by NOE and X-ray study.
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